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Publications

  • Häfeli UO, Saatchi K, Elischer P, Misri R, Bokharaei M, Labiris NR, Stoeber B (2010). Lung perfusion imaging with monosized biodegradable microspheres. Biomacromolecules 11, 561-567. link
  • Mahmoudi M, Simchi A, Imani M, Shokrgozar M, Milani A, Häfeli UO, Stroeve P (2010). A new approach for the in vitro identification of the cytotoxicity of superparamagnetic iron oxide nanoparticles. Colloids and Surfaces B: Biointerfaces 75, 300-309. link
  • Bowen ML, Chen ZF, Roos AM, Misri R, Häfeli UO, Adam MJ, Orvig C (2009). Long-chain rhenium and technetium glucosamine conjugates. Dalton Trans 9228-9236. link
  • Bowen ML, Lim NC, Ewart CB, Misri R, Ferreira CL, Häfeli UO, Adam MJ, Orvig C (2009). Glucosamine conjugates bearing N,N,O-donors: Potential imaging agents utilizing the [M(CO)3]+ core (M = Re, Tc). Dalton Trans 9216-9227. link
  • Song KY, Chiao M, Stoeber B, Häfeli U, Gupta MM, Zhang WJ (2009). Formation of uniform microspheres using a perforated silicon membrane: a preliminary study. Journal of Medical Devices 3, 034503. link
  • Saatchi K, Häfeli UO (2009). Radiolabeling of biodegradable polymeric microspheres with [99mTc(CO)3]+ and in vivo evaluation using microSPECT/CT imaging. Bioconjug Chem 20, 1209-1217. link
  • Häfeli UO, Riffle JS, Harris LA, Carmichael AY, Mark F, Dailey JP, Bardenstein D (2009). Cell uptake and in vitro toxicity of magnetic nanoparticles suitable for drug delivery. Mol Pharmaceutics 6, 1417-1428. link
  • Häfeli UO, Mokhtari A, Liepmann D, Stoeber B (2009). In vivo evaluation of a microneedle-based miniature syringe for intradermal drug delivery. Biomedical Microdevices 11, 943-950. link
  • Tokoro H, Nakabayashi T, Fujii S, Zhao H, Häfeli UO (2009). Magnetic particles with high magnetization useful for immunoassay. J Magn Magn Mater 321, 1676-1678. link
  • Zhao H, Saatchi K, Häfeli UO (2009). Preparation of biodegradable magnetic microspheres with poly(lactic acid) coated magnetite. J Magn Magn Mater 321, 1356-1363. link
  • Mahmoudi M, Shokrgozar M, Simchi A, Imani M, Milani A, Stroeve P, Vali H, Häfeli UO, Sasanpour P, Bonakdar S (2009). Multiphysics flow modeling and in vitro toxicity of iron oxide nanoparticles coated with polyvinyl alcohol. J Phys Chem C 113, 2322–2331. link
  • Mahmoudi M, Simchi A, Imani M, Häfeli UO (2009). Superparamagnetic iron oxide nanoparticles with rigid cross-linked polyethylene glycol fumarate coating for application in imaging and drug delivery. J Phys Chem C 113, 8124-8131. link
  • Saatchi K, Häfeli UO (2008). Magnetic Carriers Conference 2008. NanoMedicine 3, 415-421. link
  • Schneider T, Zhao H, Jackson JK, Chapman GH, Dykes J, Hafeli UO (2008). Use of hydrodynamic flow focusing for the generation of biodegradable camptothecin-loaded polymer microspheres. J Pharm Sci 97, 4943-4954. link
  • Saatchi K, Häfeli UO (2007). One-pot syntheses, coordination and characterization of application-specific biodegradable ligand-polymers. Dalton Trans 39, 4439-4445. link
  • Zhao H, Gagnon J, Häfeli UO (2007). Process and formulation variables in the preparation of injectable and biodegradable magnetic microspheres. Biomagn Res Technol 5:2. link
  • Häfeli UO, Gilmour K, Zhou A, Lee S, Hayden ME. Simulation and implementation of magnetic bandages for drug targeting: Button magnets versus Halbach arrays. Journal of Magnetism and Magnetic Materials 311, 323–329 (2007). link
  • Häfeli UO, Unnithan J, Pauer GJ, Prayson RA. Fibrin glue system for adjuvant brachytherapy of brain tumors with
    188    Re- and 186Re-labeled microspheres. Eur J Pharm Biopharm 65, 282-288 (2007). link
  • Hayden ME, Häfeli UO. 'Magnetic bandages' for targeted delivery of therapeutic agents. J Phys Cond Matter 18, S2877-S2891 (2006). link
  • Algur E, Macklis RM, Häfeli UO. Synergistic cytotoxic effects of zoledronic acid and radiation in human prostate cancer and myeloma cell lines. Int J Radiat Oncol Biol Phys 61, 535-542 (2005) link
  • Iacob G, Rotariu O, Strachan NJC, Häfeli UO. Magnetizable needles and wires - modeling an efficient way to target magnetic microspheres in vivo. Biorheology 41, 599-612 (2004) PDF
  • Zhang H. and Häfeli U. O., Preparation and characterization of radioactive Co/188Re stents intended for lung cancer treatment using an electrodeposition method, J. Med. Eng. Technol. 28, 197-204 (2004) link
  • Häfeli U. O., Zhang H., Bahrehmand F. and Reynaert N., Development of an automated electroplater and dosimetry system for the electrodeposition and quality control of radioactive stents, Appl. Radiat. Isot. 61, 1313-1321 (2004) link
  • Häfeli U. O., Magnetically modulated therapeutic systems, Int. J. Pharm. 277, 19-24 (2004) PDF
  • Cao J., Wang Y., Yu J., Xia J., Wang C., Yin D., Hafeli U. O., Preparation and radiolabeling of surface-modified magnetic nanoparticles with rhenium-188 for magnetic targeted radiotherapy, JMMM 277, 165-174 (2004) PDF
  • Gupta S., Adhami V. M., Subbarayan M., MacLennan G. T., Lewin J. S., Häfeli U. O., Fu P., Mukhtar, H., Suppression of prostate carcinogenesis by dietary supplementation of celecoxib in transgenic adenocarcinoma of the mouse prostate model, Cancer Res., 64 3334-3343 (2004) link
  • Häfeli U. O., Yu J., Farudi F., Li Y. and Tapolsky G., Radiolabeling of magnetic targeted carriers (MTC) with indium-111, Nuclear Medicine & Biology, 30 761-769 (2003) PDF
  • Yu J., Sands M. J., Dong Y. and Häfeli U. O., 90Y-oxine-ethiodol, a potential radiopharmaceutical for the treatment of liver cancer, Appl. Radiat. Isot., 58 567-573 (2003) link
  • Kaminski M. D., Nunez L., Ghebremeskel A. N. et al., Magnetically responsive microparticles for targeted drug and radionuclide delivery. A review of recent progress and future challenges. Argonne, IL: Argonne National Laboratory ANL-03/28, 1-92 (2003) link
  • Subbarayan M., Häfeli U. O., Feyes D. K., Unnithan J., Emancipator S. N. and Mukhtar H., A simplified method for the preparation of 99mTc-annexin V and its biological evaluation for in vivo imaging of apoptosis after photodynamic therapy, J. Nucl. Med., 44 650-656 (2003) link
  • Reynaert N. and Häfeli U. O., Response to Dr. Janicki's letter to the editor [Med. Phys. 29, 260 (2002)], Med. Phys., 29 261 (2002) link
  • Yu J. F., Häfeli U. O., Dong Y. et al., Radiolabeling of magnetic targeted carriers with several therapeutic and imaging radioisotopes, Eur. Cells Mat., 3 Suppl. 2 16-18 (2002) PDF
  • Häfeli U. O., Ciocan R. and Dailey J. P., Characterization of magnetic particles and microspheres and their magnetophoretic mobility using a digital microscopy method, Eur. Cells Mat., 3 Suppl. 2 24-27 (2002) PDF
  • Rudershausen, S., Häfeli, U. O., Grüttner, C. & Teller, J. Novel chelator containing particles specific for controlled radioisotope delivery. Journal of Labelled Compounds and Radiopharmaceuticals 44, S838-S840 (2001) PDF
  • Häfeli, U. O., Pauer, G. J. & Miller, D. D. Feasibility study for the treatment of metastatic prostate cancer with the radioactive antiandrogen I-125-bicalutamide (I-125 Casodex). Journal of Labelled Compounds and Radiopharmaceuticals 44, S670-S672 (2001)
  • Häfeli U, Pauer G, Failing S et al. Radiolabeling of magnetic particles with rhenium-188 for cancer therapy. Journal of Magnetism and Magnetic Materials 225, 73-78 (2001) PDF
  • Häfeli UO, Roberts WK, Pauer GJ et al. Preparation and stability of biodegradable radioactive rhenium microspheres (Re-186 and Re-188) for use in radiotherapy. Applied Radiation and Isotopes 54, 869-879 (2001) link
  • Erzurum VZ, Häfeli UO, Hirko MK et al. Local application of beta-particle radiation to reduce venous anastomotic intimal hyperplasia in polytetrafluorethylene arteriovenous fistulas. Vascular Surgery 34, 377-383 (2000)
  • Evans EE, Häfeli UO, Wusirika R et al. Diamond like carbon coatings for rhenium stents. Amorphous and nanostructured carbon 593, 433-438 (2000) PDF
  • Häfeli UO, Roberts WK, Meier DS et al. Dosimetry of a W-188/Re-188 beta line source for endovascular brachytherapy. Medical Physics 27, 668-675 (2000) link
  • Ciezki JP, Häfeli UO, Song P et al. Parenchymal cell proliferation in coronary arteries after PTCA: A human tissue bank study. International Journal of Radiation Oncology Biology Physics 45, 963-968 (1999) link
  • Häfeli UO, Casillas S, Dietz DW et al (1999). Radioembolization of Novikoff hepatomas using radioactive rhenium (Re-186/Re-188) glass microspheres. International Journal of Radiation Oncology Biology Physics 44, 189-199. link
  • Häfeli UO, Lee EJ, Ciezki J et al (1999). Suitability of beta-emitting rhenium for inhibiting restenosis in coronary arteries. Journal of Brachytherapy International 15, 1-11.
  • Häfeli UO, Pauer GJ. In vitro and in vivo toxicity of magnetic microspheres. Journal of Magnetism and Magnetic Materials 194, 76-82 (1999) PDF
  • Roberts WK, Häfeli UO. Modeling rhenium-186 and rhenium-188 distribution in a neutron-activated rhenium wire and effect of the distribution on beta dosimetry in a water phantom. Applied Radiation and Isotopes 51, 543-549 (1999) PDF
  • Schütt W, Grüttner C, Teller J et al. Biocompatible magnetic polymer carriers for in vivo radionuclide delivery. Artificial Organs 23, 98-103 (1999) link
  • Conzone SD, Häfeli UO, Day DE et al. Preparation and properties of radioactive rhenium glass microspheres intended for in-vivo radioembolization therapy. Journal of Biomedical Materials Research 42, 617-625 (1998) link
  • Häfeli UO, Warburton MC, Landau U. Electrodeposition of radioactive rhenium onto stents to prevent restenosis. Biomaterials 19, 925-933 (1998) link
  • Schütt W, Grüttner C, Häfeli U et al. Applications of magnetic targeting in diagnosis and therapy - possibilities and limitations. A mini-review. Hybridoma 16, 109-117 (1997) PDF
  • Gallo JM, Häfeli U. Correspondence re: A.S. Lübbe et al., Preclinical and clinical experiences with magnetic drug targeting. Cancer Research 57, 3063-3064 (1997) link
  • Häfeli UO, Pauer GJ, Macklis RM. Treatment of mouse tumors with radioactive magnetic microspheres: Model for intracavitary radiotherapy. Proceedings of the International Symposium on Controlled Release of Bioactive Materials 22, 89-90 (1995)
  • Häfeli UO, Sweeney SM, Beresford BA et al. Effective targeting of magnetic radioactive Y-90-microspheres to tumor cells by an externally applied magnetic field. Preliminary in vitro and in vivo results. Nuclear Medicine and Biology - International Journal of Radiation Applications and Instrumentation Part B 22, 147-155 (1995) PDF
  • Häfeli UO, Sweeney SM, Beresford BS et al. Biodegradable magnetically directed Y-90-microspheres: Novel agents for targeted intracavitary radiotherapy. Journal of Biomedical Materials Research 28, 901-908 (1994) link
  • Häfeli U, Atcher RW, Morris CE et al. Polymeric radiopharmaceutical delivery systems. Radioactivity & Radiochemistry 3, 11-14 (1992)
  • Häfeli U, Tiefenauer LX, Schubiger PA et al. A lipophilic complex with Re-186/Re-186 incorporated in liposomes suitable for radiotherapy. Nuclear Medicine and Biology - International Journal of Radiation Applications and Instrumentation Part B 18, 449-454 (1991) link

Book

  • Häfeli U, Schütt W, Teller J et al (1997). Scientific and clinical applications of magnetic carriers, 1st edn. Plenum, New York link

Book Chapters

  • Häfeli UO, Kale AA (2009). Topical and systemic drug delivery systems for targeted therapy. In: Cairns BE (ed) Peripheral receptor targets for analgesia: Novel approaches to pain management. John Wiley & Sons, Hoboken, NJ, USA, in press.
  • Häfeli, U. O., Aue, J. and Damani, J. (2007) The biocompatibility and toxicity of magnetic particles. In Magnetic cell separation (Zborowski, M. and Chalmers, J. J., eds.), pp. 163-223, Elsevier, Amsterdam
  • Arshady R., Pouliquen D., Halbreich A. et al., Magnetic nanospheres and nanocomposites, in: Arshady R., ed, MML Series. Vol. 5. London: Citus Books, pp. 283-328 (2002) link
  • Roffi M., Tuzcu E. M., Whitlow P. L., Häfeli U. O. and Ciezki J. P., Intravascular Ultrasound-guided catheter-based system, in: Waksman R., ed, Vascular Brachytherapy. 3rd ed. Armonk, NY: Futura Publishing Co., pp. 827-837 (2002)
  • Häfeli UO. Chapter 18: Radioactive magnetic microspheres. In: Arshady R (ed) Microspheres, Microcapsules & Liposomes: Magneto- and Radiopharmaceuticals, vol 3. Citus Books, London, 559-584 (2001) link
  • Häfeli UO. Radioactive microspheres for medical applications. In: Bulte J, de Kuyper M (eds) Focus on biotechnology. Kluwer Academic Publishing, 213-248 (2001) PDF
  • Häfeli UO. The history of magnetism in medicine. In: Andrä W, Nowak H (eds) Magnetism in medicine: A handbook. Wiley-VCH, Berlin, 15-34 (1997) link
  • Häfeli U. The mystery and history of magnetism. In: Häfeli U, Schütt W, Teller J et al (eds) Scientific and clinical applications of magnetic carriers, 1st edn. Plenum, New York, 1-10 (1997) link
  • Häfeli UO, Pauer GJ, Roberts WK et al. Magnetically targeted microspheres for intracavitary and intraspinal Y-90 radiotherapy. In: Häfeli U, Schütt W, Teller J et al (eds) Scientific and clinical applications of magnetic carriers, 1st edn. Plenum, New York, 501-516 (1997) link
  • Kraeft SK, Häfeli UO, Chen LB. Analysis of microspheres in living cells by confocal microscopy. In: Häfeli U, Schütt W, Teller J et al (eds) Scientific and clinical applications of magnetic carriers. Plenum, New York, 149-161 (1997) link
  • Häfeli U, Ciezki J, Lee E et al (1997). Development of a metallic radioactive rhenium source for the treatment of restenosis after angioplasty. In: Bryskin BD (ed) Rhenium and Rhenium Alloys. TMS (Minerals, Metals and Materials Society), Warrendale, PA, 461-468.
  • Häfeli U, German R, Pauer G et al (1997). Production of Rhenium-Powder with a jet mill and its incorporation in radioactive microspheres for the treatment of liver tumors. In: Bryskin BD (ed) Rhenium and Rhenium Alloys. TMS (Minerals, Metals and Materials Society), Warrendale, PA, 469-477.

Patents

  • Häfeli U. O., Landau U. and Warburton M. C., Method of making a radioactive stent, U.S. Patent No. 6,413,271 (July 2, 2002) link
  • Ciezki J. P., Häfeli U. O. and Bleam D., Method and apparatus for intravascular brachytherapy treatment planning, U.S. Patent No. 6,494,835 B1 (December 17, 2002) link
  • Häfeli UO, Landau U, Warburton MC. Method of making a radioactive medical device. U.S. Patent No. 6,077,413 (June 20, 2000) link
  • Lee EJ, Häfeli U, Jung EJ. Radiation source with delivery wire. U.S. Patent No. 6,024,690 (February 15, 2000) link
Last Modified: May 09, 2010.